Aims:

To perform clinical and epidemiological studies in the field of HAN and of CIF. 

To provide guidelines for HAN and for CIF. 

To participate in the education of professionals with an interest in HAN and CIF.

Composition of the group:

Core Composition:

•         a maximum of 10 members, from National PEN Societies participating to the ESPEN Council

•         the group is multidisciplinary, members are selected among pharmacists, nurses, dieticians and doctors

Composition at large:

•         any ESPEN member who proposes a study, after approval of the protocol by the group, became part of the group until the end of the study

Presentation of the works of HAN & CIF:

The coordinator of the study is normally the first author of the publication. 

Those who contributed to the study are thanked in the "acknowledgements" section. 

Papers are submitted to the ESPEN meetings and Clinical Nutrition or other relevant journals.

Meetings of the HAN & CIF group:

The group convenes for two meetings every year. The winter meeting is held during a week-end in January or February in a city of one of the members.

The second meeting takes place during the ESPEN meeting in August or September.

An open meeting is organized when appropriate during the ESPEN congress in order to give delegates the opportunity to learn about the activities of the group. The information on the web site is adjusted at half-year intervals or when appropriate.

Renewal of the group:

Members of the group must be replaced continuously in order to assure the continuity of the group. Duration of the membership is normally 3-4 years.

Proposition of new members will be based on common sense in order to maintain the multinational and multidisciplinary composition of the group.

Members must fulfill the following criteria:

• Member of ESPEN 
• Enthusiastic to participate in the work of the group
• Expertise in the field of HAN and/or CIF
• Members must be approved by their national PEN society 
• A list of the members of the HAN & CIF group will be submitted to ESPEN Central each year

Financial support:

ESPEN provides financial support. The budget has to be accepted by ESPEN Central. All expenses must be clearly defined (meetings, secretariat, mailing etc.).

Members of HAN & CIF group are encouraged to generate financial support from pharmaceuticals companies or other societies. The ESPEN treasurer will control the budget.

Activities of the group

The "CIF Action Day", the database for Chronic Intestinal Failure

Started in 2015, the database has received the contribution of more than 126 of centers from 27 Countries, enrolling around 7000 patients, adults and children.FailureNew Centers that would like to join the database have to send a request to the study coordinator (Loris Pironi) at espencifday@gmail.com , with the following data: 

• First name
• Middle initial(s)
• Surname
• Affilation:
• Hospital name
• City
• Country
• Address
• Phone
• Fax
• e-Mail
• CIF age category in your center (adult, pediatric or both)
• Year of starting HPN activity

They will recieve the study protocol and the database for the data collection 

 

Home Parenteral Nutrition Book - 2nd edition    

Containing contributions from leading international experts and under the auspices of the ESPEN HAN Group, this book explores the life-saving treatment of home parenteral nutrition. It covers the complete scenario of home parenteral nutrition (HPN), from its prevalence in different continents to clinical indications and the practical aspects of its management. Topics covered inlcude the growing use of HPN, scientific and practical issues associated with HPN in adults and the pediatric population, indications and outcomes in various diseases, complications, nutrient requirements, preparation and administration of the admixtures, monitoring of patients, medical and surgical alternatives, ethics and legislation, and quality of life. To order it, click here.

ESPEN LLL-course on Home Parenteral Nutrition in Adults

The group actively contributes to the ESPEN LLL program by delivering the course on HPN in adults.

Acknowledgments

The group has been awarded with the “ESPEN RESEARCH NETWORK GRANT” 2009 for the project: “An international study of the quality of life of adult patients treated with home parenteral nutrition (HPN)”, presented by Janet Baxter.

 

Publications    

Pironi L. Home Artificial Nutrition and Chronic Intestinal Failure SpecialInterest Group of ESPEN. Revised ESPEN Clinical Classification of ChronicIntestinal Failure: From 16 to 8 Categories. JPEN J Parenter Enteral Nutr. 2017Aug;41(6):911. doi: 10.1177/0148607117722757. PubMed PMID: 28972458.

Joly F, Baxter J, Staun M, Kelly DG, Hwa YL, Corcos O, De Francesco A,Agostini F, Klek S, Santarpia L, Contaldo F, Jonker C, Wanten G, Chicharro L,Burgos R, Van Gossum A, Cuerda C, Virgili N, Pironi L; ESPEN HAN CIF group. Five-year survival and causes of death in patients on home parenteral nutritionfor severe chronic and benign intestinal failure. ClinNutr. 2017 Jun 19. pii:S0261-5614(17)30227-3. doi: 10.1016/j.clnu.2017.06.016. [Epub ahead of print]PubMed PMID: 28701261.

Pironi L, Konrad D, Brandt C, Joly F, Wanten G, Agostini F, Chambrier C,Aimasso U, Zeraschi S, Kelly D, Szczepanek K, Jukes A, Di Caro S, Theilla M,Kunecki M, Daniels J, Serlie M, Poullenot F, Wu J, Cooper SC, Rasmussen HH,Compher C, Seguy D, Crivelli A, Pagano MC, Hughes SJ, Guglielmi FW, Kozjek NR, Schneider SM, Gillanders L, Ellegard L, Thibault R, Matras P, Zmarzly A, MatysiakK, Van Gossum A, Forbes A, Wyer N, Taus M, Virgili NM, O'Callaghan M, Chapman B, Osland E, Cuerda C, Sahin P, Jones L, Lee ADW, Bertasi V, Orlandoni P, Izbéki F, Spaggiari C, Díez MB, Doitchinova-Simeonova M, Garde C, Serralde-Zúñiga AE, Olveira G, Krznaric Z, Czako L, Kekstas G, Sanz-Paris A, Jáuregui EP, Murillo AZ, Schafer E, Arends J, Suárez-Llanos JP, Shaffer J, Lal S. Clinical classification of adult patients with chronic intestinal failure due to benign disease: Aninternational multicenter cross-sectional survey. ClinNutr. 2018Apr;37(2):728-738. doi: 10.1016/j.clnu.2017.04.013. Epub 2017 Apr 19. PubMedPMID: 28483328.

Pironi L, Arends J, Bozzetti F, Cuerda C, Gillanders L, Jeppesen PB, Joly F, Kelly D, Lal S, Staun M, Szczepanek K, Van Gossum A, Wanten G, Schneider SM; HomeArtificial Nutrition & Chronic Intestinal Failure Special Interest Group ofESPEN. Corrigendum to "ESPEN guidelines on chronic intestinal failure in adults" [ClinNutr 35 (2) (2016) 247-307]. ClinNutr. 2017 Apr;36(2):619. doi:10.1016/j.clnu.2016.12.008. Epub 2016 Dec 23. PubMed PMID: 28027797.

Van Gossum A, Pironi L, Chambrier C, Dreesen M, Brandt CF, Santarpia L, JolyF. Home parenteral nutrition (HPN) in patients with post-bariatric surgerycomplications. ClinNutr. 2017 Oct;36(5):1345-1348. doi:10.1016/j.clnu.2016.08.025. Epub 2016 Sep 8. PubMed PMID: 27642058.

Cuerda C, Pironi L; Home Artificial Nutrition and Chronic Intestinal FailureSpecial Interest Group of ESPEN. Reply, Letter to the Editor – Primarythromboprophylaxis for adult patients on home parenteral nutrition: A comment on the 2016 ESPEN guideline. ClinNutr. 2016 Dec;35(6):1581-1582. doi:10.1016/j.clnu.2016.08.001. Epub 2016 Aug 10. PubMed PMID: 27544409.

Pironi L, Shaffer J; Home Artificial Nutrition & Chronic Intestinal Failureand the Acute Intestinal Failure Special Interest Groups of ESPEN. Reply toLetter to the Editor - Intestinal failure definition and classification comments.ClinNutr. 2016 Jun;35(3):763. doi: 10.1016/j.clnu.2016.03.022. Epub 2016 Apr 4. PubMed PMID: 27075320.

Pironi L, Arends J, Bozzetti F, Cuerda C, Gillanders L, Jeppesen PB, Joly F,Kelly D, Lal S, Staun M, Szczepanek K, Van Gossum A, Wanten G, Schneider SM; HomeArtificial Nutrition & Chronic Intestinal Failure Special Interest Group ofESPEN. ESPEN guidelines on chronic intestinal failure in adults. ClinNutr. 2016 Apr;35(2):247-307. doi: 10.1016/j.clnu.2016.01.020. Epub 2016 Feb 8. PubMed PMID:26944585.

Cuerda C, Joly F, Corcos O, Concejo J, Puiggrós C, Gil C, Pironi L; HAH-CIF ESPEN Group. Prospective study of catheter-related central vein thrombosis in home parenteral nutrition patients with benign disease using serial venous Doppler ultrasound. ClinNutr. 2016 Feb;35(1):153-7. doi: 10.1016/j.clnu.2015.01.011. Epub 2015 Jan 23. PubMed PMID: 25660318.

Pironi L, Arends J, Baxter J, Bozzetti F, Peláez RB, Cuerda C, Forbes A, Gabe S, Gillanders L, Holst M, Jeppesen PB, Joly F, Kelly D, Klek S, Irtun Ø, OldeDamink SW, Panisic M, Rasmussen HH, Staun M, Szczepanek K, Van Gossum A, Wanten G, Schneider SM, Shaffer J; Home Artificial Nutrition & Chronic Intestinal Failure and the Acute Intestinal Failure Special Interest Groups of ESPEN. ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. ClinNutr. 2015 Apr;34(2):171-80.

Dreesen M, Pironi L, Wanten G, Szczepanek K, Foulon V, Willems L, Gillanders L, Joly F, Cuerda C, Van Gossum A. Outcome Indicators for Home Parenteral Nutrition Care: Point of View From Adult Patients With Benign Disease. JPEN J Parenter Enteral Nutr. 2015 Sep;39(7):828-36. doi: 10.1177/0148607114536926. Epub 2014 Jun 10. PubMed PMID: 24917517.

Van Gossum A, Pironi L, Messing B, Moreno C, Colecchia A, D'Errico A, Demetter P, De Gos F, Cazals-Halem D, Joly F. Transient Elastography (FibroScan) Is Not Correlated With Liver Fibrosis but With Cholestasis in Patients With Long-Term Home Parenteral Nutrition. JPEN J Parenter Enteral Nutr. 2015 Aug;39(6):719-24. doi: 10.1177/0148607114538057. Epub 2014 Jun 9. PubMed PMID: 24913657.

Bozzetti F, Santarpia L, Pironi L, Thul P, Klek S, Gavazzi C, Tinivella M, Joly F, Jonkers C, Baxter J, Gramlich L, Chicharro L, Staun M, Van Gossum A, Lo Vullo S, Mariani L. The prognosis of incurable cachectic cancer patients on home parenteral nutrition: a multi-centre observational study with prospective follow-up of 414 patients. Ann Oncol. 2014 Feb;25(2):487-93.

Dreesen M, Foulon V, Hiele M, Vanhaecht K, De Pourcq L, Pironi L, Van Gossum A, Arends J, Cuerda C, Thul P, Bozzetti F, Willems L. Quality of care for cancer patients on home parenteral nutrition: development of key interventions and outcome indicators using a two-round Delphi approach. Support Care Cancer. 2013 May;21(5):1373-81.

Pironi L, Baxter JP, Lauro A, Guidetti M, Agostini F, Zanfi C, Pinna AD. Assessment of quality of life on home parenteral nutrition and after intestinal transplantation using treatment-specific questionnaires. Am J Transplant. 2012 Dec;12 Suppl 4:S60-6.

Baxter JP, Gillanders L, Angstmann K, Staun M, O’Hanlon C, Smith T, Joly F, Thul P, Jonkers C, Wanten G, Gardiner K, Klek S, Cuerda C, Magambo W, Hawthorne AB, Lukes A, Van Gossum A, Theilla M, Singer P, Shamir R, Pironi L. Home parenteral nutrition: An international benchmarking exercise. E-SPEN Journal 7 (2012) e211-e214

Pironi L, Goulet O, Buchman A, Messing B, Gabe S, Candusso M, Bond G, Gupte G, Pertkiewicz M, Steiger E, Forbes A, Van Gossum A, Pinna AD; Home Artificial Nutrition and Chronic Intestinal Failure Working Group of ESPEN. Outcome on home parenteral nutrition for benign intestinal failure: a review of the literature and benchmarking with the European prospective survey of ESPEN. ClinNutr. 2012 Dec;31(6):831-45.

Dreesen M, Foulon V, Vanhaecht K, Hiele M, De Pourcq L, Pironi L, Van Gossum A, Wanten G, Baxter JP, Joly F, Cuerda C, Willems L. Development of quality of care interventions for adult patients on home parenteral nutrition (HPN) with a benign underlying disease using a two-round Delphi approach. ClinNutr. 2013 Feb;32(1):59-64.

Pironi L, Forbes A, Van Gossum A. Gut. 2012 Jan;61(1): author reply 167.

Pironi L, Joly F, Forbes A, Colomb V, Lyszkowska M, Baxter J, Gabe S,Hébuterne X, Gambarara M, Gottrand F, Cuerda C, Thul P, Messing B, Goulet O, Staun M, Van Gossum A; Home Artificial Nutrition & Chronic Intestinal Failure Working Group of the European Society for Clinical Nutrition and Metabolism (ESPEN). Long-term follow-up of patients on home parenteral nutrition in Europe: implications for intestinal transplantation. Gut. 2011 Jan;60(1):17-25.

Pironi L, Staun M, Van Gossum A. Intestinal transplantation. N Engl J Med.2009 Dec 10;361(24):2388-9; author reply 2389.

Staun M, Pironi L, Bozzetti F, Baxter J, Forbes A, Joly F, Jeppesen P, Moreno J, Hébuterne X, Pertkiewicz M, Mühlebach S, Shenkin A, Van Gossum A; ESPEN. ESPEN Guidelines on Parenteral Nutrition: home parenteral nutrition (HPN) in adult patients. ClinNutr. 2009 Aug;28(4):467-79.

Pironi L, Forbes A, Joly F, Colomb V, Lyszkowska M, Van Gossum A, Baxter J,Thul P, Hébuterne X, Gambarara M, Gottrand F, Moreno Villares JM, Messing B,Goulet O, Staun M; Home Artificial Nutrition Working Group of the European Society for Clinical Nutrition and Metabolism (ESPEN). Survival of patients identified as candidates for intestinal transplantation: a 3-year prospective follow-up. Gastroenterology. 2008 Jul;135(1):61-71.

Staun M, Hebuterne X, Shaffer J, Haderslev KV, Bozzetti F, Pertkiewicz M, Micklewright A, Moreno J, Thul P, Pironi L. Management of intestinal failure in Europe. A questionnaire based study on the incidence and management. Dyn Med. 2007 Jul 4;6:7.

Pironi L, Hébuterne X, Van Gossum A, Messing B, Lyszkowska M, Colomb V, Forbes A, Micklewright A, Villares JM, Thul P, Bozzetti F, Goulet O, Staun M. Candidates for intestinal transplantation: a multicenter survey in Europe. Am J Gastroenterol. 2006 Jul;101(7):1633-43.

Wengler A, Micklewright A, Hébuterne X, Bozzetti F, Pertkiewicz M, Moreno J, Pironi L, Thul P, Van Gossum A, Staun M; ESPEN-Home Artificial Nutrition working group. Monitoring of patients on home parenteral nutrition (HPN) in Europe: a questionnaire based study on monitoring practice in 42 centres. ClinNutr. 2006 Aug;25(4):693-700.

Pironi L, Tjellesen L, De Francesco A, Pertkiewicz M, MorselliLabateAM,Staun M, Przedlacki J, Lezo A, Orlandoni P, Pasanisi F; ESPEN-home artificial nutrition working group. Bone mineral density in patients on home parenteral nutrition: a follow-up study. ClinNutr. 2004 Dec;23(6):1288-302.

Hébuterne X, Bozzetti F, Moreno Villares JM, Pertkiewicz M, Shaffer J, Staun M, Thul P, Van Gossum A; ESPEN-Home Artificial Nutrition Working Group. Home enteral nutrition in adults: a European multicentre survey. ClinNutr 2003;22:261-6

Bozzetti F, Mariani L, Bertinet DB, Chiavenna G, Crose N, De Cicco M, Gigli G, Micklewright A, Moreno Villares JM, Orban A, Pertkiewicz M, Pironi L, Vilas MP, Prins F, Thul P. Central venous catheter complications in 447 patients on home parenteral nutrition: an analysis of over 100.000 catheter days. ClinNutr. 2002 Dec;21(6):475-85.

Pironi L, Labate AM, Pertkiewicz M, Przedlacki J, Tjellesen L, Staun M, De Francesco A, Gallenca P, Guglielmi FW, Van Gossum A, Orlandoni P, ContaldoF,Villares JM; Espen-Home Artificial Nutrition Working Group. Prevalence of bone disease in patients on home parenteral nutrition. ClinNutr. 2002 Aug;21(4):289-9.

Van Gossum A, Vahedi K, Abdel-Malik, Staun M, Pertkiewicz M, Shaffer J,Hébuterne X, Beau P, Guédon C, Schmit A, Tjellesen L, Messing B, Forbes A. Clinical, social and rehabilitation status of long-term home parenteral nutrition patients: results of a European multicentre survey. ClinNutr 2001;20:205-10

Moreno JM, Shaffer J, Staun M, Hébuterne X, Bozzetti F, Pertkiewicz M, Thul P, Van Gossum A. Survey on legislation and funding of Home Artificial Nutrition in different european countries. ClinNutr 2001;20:117-23

Van Gossum A, Bakker H, Bozzetti F, Staun M, Leon-Sanz M, Hébuterne X, Pertkiewicz M, Shaffer J, Thul P. Home parenteral nutrition in adults: A europeanmulticentre survey in 1997. ESPEN-Home Artificial Nutrition Working Group. ClinNutr 1999;18:135-40

Van Gossum A. et al. Home Parenteral Nutrition (HPN) in children. A multicentre survey in Europe in 1997. ClinNutr 1998;17(suppl. 1):49

Shaffer J. et al. A European survey on management of metabolic complications in home parenteral nutrition.  ClinNutr 1997; 16 (suppl. 2):73

Van Gossum A, Bakker H, De Francesco A, Ladefoged K, Leon-Sanz M, Messing B, Pironi L, Pertkiewicz M, Shaffer J, Thul P, Wood S. ESPEN-Home Artificial Nutrition Working Group.  Home parenteral nutrition in adults: a multicentre survey in Europe in 1993. ClinNutr. 1996 Apr;15(2):53-9.

Studies in progress      For more information and participation, please contact the study coordinator. European consensus definition, diagnosis and categorisation of Intestinal Failure Associated Liver Disease (IFALD) in adults (coordinator: Simon Lal) Recommendations on selection criteria for trophic factor treatment and on treatment management of patients with SBS-CIF (coordinator: Francisca Joly) Attitude of physicians on nutritional support in patients with head–neck cancer (coordinators: Federico Bozzetti, Andrè Van Gossum) Survey on clinicians’ perspective on CIPO management in collaboration with ESNM (coordinator: Simon Lal) Clinician attitudes towards the use of home parenteral nutrition for adult patients with advanced malignancy. (coordinator: Simon Lal)     HAN & CIF Working Group     Chairman HAN & CIF Working Group Chairman Prof. Loris PIRONI Center for Chronic Intestinal Failure, St. Orsola-Malpighi Hospital University of Bologna Via Massarenti, 9 40138 Bologna, Italy TEL/FAX: +39 - 051 - 6363073   Members Prof. Dr. med. Georg LAMPRECHT Division of Gastroenterology and Endocrinology, Dep. of Internal Medicine University Medical Center Rostock georg.lamprecht@med.uni-rostock.de Tele: 49 (0) 381 494 7481 Fax: 49 (0) 381 494 7482 Universitätsmedizin Rostock Ernst-Heydemann-Str. 6 18057 Rostock Germany Dr. Cristina CUERDA Nutrition Unit Hospital General Universitario Gregorio Marañón c/ Doctor Esquerdo 46 28007 Madrid, Spain FAX: +34 915868018 Dr. Francisca JOLY Department of Gastroenterology and Nutritional Support Approved centre for intestinal failure Hôpital Beaujon 100 Bd General Leclerc 92110 Clichy, France Dr. Simon LAL Intestinal Failure Unit Salford Royal Foundation Trust Salford U.K. M68HD Simon.Lal@srft.nhs.uk TEL: +41 01612065147 ____________________ Dr. Michael STAUN Rigshospitalet Department of Medical Gastroenterology CA2121 Blegdamsvej 9 DK-2100 Copenhagen, Denmark TEL: +45 3545 2157 FAX: +45 3545 2913 Dr. Kinga Szczepanek Department of Anaesthesiology and Intensive Care Medicine Jagiellonian University Collegium Medicum Krakow Poland TEL: +48 608 515 670 Prof. Andrè Van Gossum Université Libre de Bruxelles Erasme Hospital Gastroenterology Department Route de Lennik 808  1070 BRUXELLES  Belgium  Tel.: +32 2 555 4900  Fax: +32 2 555 4901  Dr. Geert WANTEN Intestinal Failure Unit Department of Gastroenterology and Hepatology Radboud University Nijmegen Medical Centre P.O. Box 9101 6500 HB Nijmegen, The Netherlands Phone: ++31 24 3614760 Fax: ++31 24 3540103